Optimise your Phase II trial before enrolling a single patient.

Simulate different doses, patient populations and trial designs across virtual patients to identify the approaches with the best chance of success. Now available for NSCLC and PD-1 / PD-L1 inhibitors.

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Get early access

Interested in using Causomic? We’re partnering with a small number of teams to validate our NSCLC trial simulation model.

01

Add your drug model

Bring your compound and relevant clinical data.

02

Run virtual Phase II trials

Simulate your trial across thousands of virtual patients.

03

Compare & optimise designs

Explore different trial designs and identify the most promising approach.

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Start from a model calibrated to your compound

Bring the compound and what is known about it — mechanism of action, preclinical data, Phase I PK/PD, the indication. What comes back is a model of that compound: it has to reproduce what has already been observed before it is allowed to project anything. Every virtual patient below is dosed with it.

Illustrative calibration on simulated data.

Test protocols across realistic patient populations

Simulate each protocol across thousands of virtual patients, varying eligibility criteria, biomarkers and patient characteristics to understand how each design performs across realistic populations.

Protocols · Virtual patients · Simulated outcomes

Illustrative NSCLC cohort. These are simulation outputs, not results from a clinical trial.

Find the trial design with the best chance of success

Explore and compare thousands of possible Phase II designs across the same virtual population, before enrolling a single patient.

Simulated Trial Designs Simulated design Top-ranked design
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